MGM Cancer Institute performs first half-matched transplant

Setting a new milestone in pediatric transplantation, MGM Cancer Institute has saved the life of a 12-year-old girl with Bloom Syndrome, a rare genetic disorder, by performing a complex procedure known as TCR alpha beta depleted haploidentical bone marrow transplant (BMT), using life-saving stem cells from her younger brother. This marks the first documented success of such a transplant in a pediatric patient anywhere in the world. 

The surgical team was headed by Dr. M. Deenadayalan, HOD and Clinical Lead, Department of Paediatric Haematology, Oncology, Blood and Marrow Transplantation. In his comments, Dr. Deenadayalan, said, “To our knowledge, this is world’s only documented successful TCR alpha beta depleted haploidentical bone marrow transplant in a child with Bloom Syndrome. We are proud of our team’s expertise in carrying out one of the most challenging bone marrow transplants ever attempted.” The patient is now attending school regularly and participating in daily activities like other children her age. However, she will continue to be under regular medical follow-up to monitor her long-term health.